Research & Scientists | People | JAPALHA


Name: Joana Palha

Office: G2.30

School Phone: +351 253 604 817

Email: japalha@med.uminho.pt




Keywords: Choroid plexus blood-brain barrier cerebrospinal fluid thyroid hormones aging


Joana Palha (PhD, born 1969) is full professor in the medical school, School of Medicine, University of Minho, Braga, Portugal and vice-dean for postgraduate studies.

She is a neuroscientist, with work focused mostly in the barriers of the brain, and in the study of genetic and biochemical determinants of aging and neuropsychiatric disorders.

She presently serves at the scientific board of the Portuguese Science Foundation (FCT) and at the SFN (Society for Neurosciences, USA). She has served  at the IBRO (International Brain Research Organization) and was a COST Committee of Senior Officials, and a delegate for the COST Biomedicine and Molecular Biosciences; and was secretary of the Portuguese Society for Neurosciences. She has been part of the jury of several international prizes and committees.

She has reviewed fornational (Portuguese Science Foundation) and international funding agencies (European Commission; National Science Foundation, USA; Alzheimer’s Research Foundation; Fulbright;Research Council, UK).

She is associate editor of Frontiers in Neurosciences, and is reviewer in several journals.

She has published over 90 articles in peered-reviewed journals.


Communication across the barriers (Leader) 

Maintaining health in old age through homeostasis (Switchbox)  


Neural cells modulation and support  

The role of the immune system in mood disorders and cognition  

Selected Publications

Ferreira AC, Mesquita SD, Sousa JC, Correia-Neves M, Sousa N, Palha JA, Marques F. From the periphery to the brain: lipocalin-2, a friend or foe? Prog Neurobiol, 131:120-136 (2015).

Aslani S, Harb MR, Costa PS, Almeida OF, Sousa N, Palha JA. Day and night: diurnal phase influences the response to chronic mild stress. Front Behav Neurosci, 8:82 (2014).

Mesquita SD, Ferreira AC, Gao F, Coppola G, Geschwind DH, Sousa JC, Correia-Neves M, Sousa N, Palha JA, Marques F. The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease. Brain Behav Immun, in press.

Aslani S, Vieira N, Marques F, Costa PS, Sousa N, Palha JA. The effect of high fat diet on rat’s mood, feeding behavior and response to stress. Transl Psychiat, 5:e684 (2015).

Marques F, Sousa JC, Sousa N, Palha JA. Blood–brain-barriers in aging and in Alzheimer’s disease. Mol Neurodegener, 8:38 (2013).

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