Research & Scientists | Neurosciences | People | JOANAMSILVA


Name: Joana Silva

Office: I2.03

School Phone: +351 253 604 835

Email: q9688@med.uminho.pt




Keywords: Neurodegneration Proteostasis Tau Alzheimer Stress Behavior Cognition


Joana Silva is a Post-Doc Researcher at ICVS/3B’s PT-Government Associate Laboratory, in the School of Medicine Science, University of Minho. Her main line of research is related with the mechanisms involved in the development of neurodegenerative disorders, mainly directed to the role of Tau protein in the development of Alzheimer's Disease and Tauopathies. Her Master and PhD studies have been focused on the role of Tau protein in the progression and development of neurodegeneration, through the mechanisms involved in regulation of protein degradation and aggregation and their involvement in cell death processes like apoptosis and autophagy. Moreover, she is interested in the interaction between SGs and Tau pathology in the context of stress-driven neurodegeneration, novel mechanisms described to be relevant in AD. Joana is currently enrolled in a project focused on the role of Tau in the brain development and brain aging as well as initiation of neurodegeneration using novel transgenic mice models. 


Sensomotor mechanisms and Alzheimer´s disease pathology  

Selected Publications

Moreira PS, Sotiropoulos I, Silva J, Takashima A, Sousa N, Leite-Almeida H, Costa PS. The advantages of Structural Equation Modelling to address the complexity of spatial reference learning. Front Behav Neurosci, 10:18 (2016).

Pinheiro S, Silva J, Mota C, Vaz-Silva J, Veloso A, Pinto V, Sousa N, Cerqueira J, Sotiropoulos I. Tau mislocation in glucocorticoid-triggered hippocampal pathology. Mol Neurobiol, 53(7):4745-4753 (2016)

Vyas S, Rodrigues AJ, Silva JM, Tronche F, Almeida OFX, Sousa N, Sotiropoulos I. Chronic Stress and Glucocorticoids: from neuronal plasticity to neurodegeneration. Neural Plasticity, 2016:6391686 (2016).

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