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about icvs | People | NUNOSILVA

 

Name: Nuno A. Silva

Office: I2.02

School Phone: +351 604 839

Email: nunosilva@med.uminho.pt

 

 

 

Keywords: Spinal Cord Injury Regenerative Medicine

About

Nuno Silva completed his BSc in Applied Biology in 2007 and received his PhD in Tissue Engineering, Regenerative Medicine and Stem Cells from the University of Minho in 2012. His PhD work consisted on the development of novel approaches for Spinal Cord Injury Repair based on biodegradable materials and stem cells. His PhD was carried out in the 3B’s Research Group, in the Life and Health Sciences Research Institute (ICVS), both from the University of Minho, and in the Centre for Cellular and Biomolecular Research of the University of Toronto.

In 2012 he started a post-doc at ICVS dedicated to study the best therapeutic combination to treat the injured spinal cord. In 2014 he was able to capture national competitive funding and started his own lab. In 2019 his position was reinforced through a FCT CEEC grant (Assistant Researcher - CEECIND/04794/2017). The concept of his lab is based on an intimate cross talk between pharmacotherapies, stem cells, biomaterials and basic neuroscience. The team is presently constituted by 1 post-doctoral fellows, 1 MD-PhD student and 3 PhD students. He is currently an author of 48 papers published in international peer-reviewed journals. Nuno Silva has currently more than 2200 citations and an h-index of 22. Additionally he is author of 7 book chapters and has more than 60 communications in national and international conferences. He supervises/supervised 19 post-graduation students. Parallel to his research activity his has been acting as referee for several international journals and for the European Science Foundation. He was part of the scientific and organizing committees of the Spinal Cord Iberian Symposium (SCiS 2015) and was the meeting chair of the first Minho Spinal Cord Injury Meeting (MiSCI-2019). Finally, during his research career, Nuno Silva was able to capture more than 1 million Euros of competitive funding, either as salary grants (438k) or in research projects (645k). Currently, he is managing as a Principal Investigator one FCT Project (239k) and, as co-Principal Investigator, the Melo e Castro Award 2021 (66k).

Projects

Hybrid - Templates for Peripheral Nerve Regeneration  

Multidisciplinary Strategies for Spinal Cord Injury Repair  

Selected Publications

Silva NA, Sousa N, Reis RL, Salgado AJ. From Basics to Clinical: A Comprehensive Review on Spinal Cord Injury. Prog Neurobiol, 114:25-57 (2014).

Silva NA, Cooke MJ, Tam RY, Sousa N, Salgado AJ, Reis RL, Shoichet MS. The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate. Biomaterials. 2012 Sep;33(27):6345-54. doi: 10.1016/j.biomaterials.2012.05.050. Epub 2012 Jun 12.

Silva NA, Gimble JM, Sousa N, Reis RL, Salgado AJ. Combining Adult Stem Cells and Olfactory Ensheathing Cells: The Secretome Effect. Stem Cells and Development. April 15, 2013, 22(8): 1232-1240. doi:10.1089/scd.2012.0524.

Silva NA, Moreira J, Ribeiro-Samy S, Gomes E, Tam RY, Shoichet MS, Reis R, Sousa N, Salgado A. Modulation of Bone Marrow Mesenchymal Stem Cell Secretome by ECM-Like Hydrogels. Biochimie, 95:2314-2319 (2013).

Ribeiro-Samy S, Silva NA, Correlo VM, Fraga JS, Pinto L, Teixeira-Castro AC, Leite-Almeida H, Almeida A, Gimble JM, Sousa N, Salgado AJ, Reis RL. Development and Characterization of PHB-HV based 3D Scaffolds for a Tissue Engineering and Cell-Therapy Combinatorial Approach for Spinal Cord Injury Regeneration. Macromolecular Biosience, (2013), in press

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