about icvs | People | JOAOOLIVEIRA


Name: João Filipe Oliveira

Office: I2.12

School Phone: +351 253 604 871

Email: joaooliveira@med.uminho.pt




Keywords: astrocyte behavior cognition depression electrophysiology


João Filipe Oliveira (PhD) graduated as Pharmaceutical Sciences in 2004,at the Faculty of Pharmacy – University of Porto. He obtained his PhD degree in 2009 from the Medicine Faculty – University of Leipzig, in Germany under the supervision of Prof. Peter Illes.

João Filipe Oliveira received a Marie Curie Fellow (FP7-PEOPLE-2010-IEF273936 STRESSEDASTROCYTES) to integrate the Institute of Health and Life Sciences Research, University of Minho, where he is currently Principal Investigator on the topic "Astrocyte involvement in behavior, in health and disease".

João Filipe Oliveira is last/corresponding author in several scientific reports. He has been invited to talk at national and international congresses. He is currently supervising post-doc and MSc and PhD students.

João Filipe Oliveira is the coordinator of the Portuguese Glial Network and he is a member of the Portuguese Society of Neuroscience, FENS and SfN.

João Filipe Oliveira has been awarded research grants, fellowships, and contracts, namely the DAAD PhD Scholarship (2005) and Marie Curie Intra-European Fellowship (2011). He is frequently invited for reviewing grant and article proposals by international funding agencies and Scientific Journals.

Relevant publications:

Escartin C*, Galea E*, Lakatos A, O’Callaghan JP, PetzoldGC, Serrano-Pozo A, Steinhauser C, Volterra A, Carmignoto G,Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, Bonvento G,Butt AM, Chen WT, Cohen-Salmon M, Cunningham C, Deneen B, De Strooper B,Díaz-Castro B, Farina C, Freeman M, Gallo V, Goldman JE, Goldman SA, Götz M,Gutiérrez A, Haydon PG, Heiland DH, Hol EM, Holt MG, Iino M, Kastanenka KV, KettenmannH, Khakh BS, Koizumi S, Lee CJ, Liddelow SA, MacVicar BA, Magistretti P,Messing A, Mishra A, Molofsky AV, Murai K, Norris CM, Okada S, Oliet SHR,Oliveira JF, Panatier A, Parpura V, Pekna M, Pekny M, PellerinL, Perea G, Pérez-Nievas BG, Pfrieger FW, Poskanzer KA, Quintana FJ, RansohoffRM, Riquelme-Perez M, Robel S, Rose CR, Rothstein J, Rouach N, Rowitch DH,Semyanov A, Sirko S, Sontheimer H, Swanson RA, Vitorica J, Wanner IB, WoodLB, Wu J, Zheng B, Zimmer ER, Zorec R, Sofroniew MV*, Verkhratsky A*. Reactive astrocyte nomenclature, definitions, andfuture directions. Nature Neuroscience. 2021. In press. doi: 10.1038/s41593-020-00783-4

Falcon-Moya et al., Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
Nature Communications in press

BatiukMY, Martirosyan A, Wahis J, Vin F de, Marneffe C, Kusserow C, Koeppen J, VianaJF, Oliveira JF, Voet T, Ponting CP, Belgard TG, Holt MG. 2020.Identification of region-specific astrocyte subtypes at single cell resolution.Nature Communications 11:1–15.

Duarte JM, Gaspar R, Caetano L, Patrício P,Soares-Cunha C, Mateus-Pinheiro A, Alves ND, Santos AR, Ferreira SG, SardinhaV, Oliveira JF, Fontes-Ribeiro C,Sousa N, Cunha RA, Ambrósio AF, Pinto L, Rodrigues AJ, Gomes CA. 2019. Region-specific control of microglia byadenosine A2A receptors: uncoupling anxiety and associated cognitive deficitsin female rats. Glia. 67:182–192.

Guerra-Gomes S, Viana JF, Correia JS, Caetano I, Sardinha VM, Sousa N, Pinto L, Oliveira JF (2018). The role of astrocytic calcium signaling in the aged prefrontal cortex. Front. Cell. Neurosci. 12.

Guerra-Gomes S, Sousa N, Pinto L, Oliveira JF (2018) Functional roles of astrocyte calcium elevations: from synapses to behavior. Front Cell Neurosci 11:427.

Kafetzopoulos V, Kokras N, Sotiropoulos I, Oliveira JF, Leite-Almeida H, Vasalou A, Sardinha VM, Papadopoulou-Daifoti Z, Almeida OFX, Antoniou K, Sousa N, Dalla C (2018) The nucleus reuniens: a key node in the neurocircuitry of stress and depression. Molecular Psychiatry 23:579–586.

Sardinha VM, Guerra-Gomes S, Caetano I, Tavares G, Martins M, Reis JS, Correia JS, Teixeira-Castro A, Pinto L, Sousa N, Oliveira JF (2017) Astrocytic signaling supports hippocampal–prefrontal theta synchronization and cognitive function. Glia 65:1944–1960.

Mateus-Pinheiro A, Alves ND, Patrício P, Machado-Santos AR, Loureiro-Campos E, Silva JM, Sardinha VM, Reis J, Schorle H,
 Oliveira JF, Ninkovic J, Sousa N, Pinto L (2016) AP2? controls adult hippocampal neurogenesis and modulates cognitive, but not anxiety or depressive-like behavior. Mol Psychiatry. doi: 10.1038/mp.2016.169 In press

Caetano L, Pinheiro H, Patrício P, Mateus-Pinheiro A, Alves ND, Coimbra B, Baptista FI, Henriques SN, Cunha C, Santos AR, Ferreira SG, Sardinha VM,
Oliveira JF, Ambrósio AF, Sousa N, Cunha RA, Rodrigues AJ, Pinto L, Gomes CA (2017) Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety. Mol Psychiatry 22:1035–1043.

Tavares G, Martins M, Correia JS, Sardinha VM, Guerra-Gomes S, Neves SP das, Marques F, Sousa N,
 Oliveira JF. (2017) Employing an open-source tool to assess astrocyte tridimensional structure. Brain Struct Funct 222:1989–1999.

Oliveira JF, Gomes CA, Vaz SH, Sousa N, Pinto L (2016) Editorial: Glial Plasticity in Depression. Frontiers in Cellular Neuroscience 10

Oliveira JF, Sardinha VM,Guerra-Gomes S, Araque A, Sousa N (2015) Do stars govern our actions? Astrocyte involvement in rodent behavior. (2015) Trends Neurosci 38:535–549. 

Lima A, Sardinha VM, Oliveira AF, Reis M, Mota C, Silva MA, Marques F, Cerqueira JJ,Pinto L, Sousa N, Oliveira JF (2014) Astrocyte pathology in theprefrontal cortex impairs the cognitive function of rats. Molecular Psychiatry 19, 834–841.

Oliveira, J.F.,Dias, N.S., Correia, M., Gama-Pereira, F., Sardinha, V.M., Lima, A., Oliveira,A.F., Jacinto, L.R., Ferreira, D.S., Silva, A.M., et al. (2013).Chronic stress disrupts neural coherence between cortico-limbic structures.Frontiers in Neural Circuits 7.

Teixeira-CastroA, Ailion M, Jalles A, Brignull HR, Vilaça JL, Dias N, Rodrigues P, OliveiraJF, Neves-Carvalho A, Morimoto RI, Maciel P (2011) Neuron-specificproteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1pathways. Hum Mol Genet 20:2996–3009.

Oliveira JF,Riedel T, Leichsenring A, Heine C, Franke H, Krügel U, Nörenberg W, Illes P(2011) Rodent cortical astroglia express in situ functional P2X7 receptorssensing pathologically high ATP concentrations. Cereb. Cortex 21:806-820.

Oliveira JF,Krügel U, Köles L, Illes P, Wirkner K (2008)  Blockade of glutamatetransporters leads to potentiation of NMDA receptor current in layer Vpyramidal neurons of the rat prefrontal cortex via group II metabotropicglutamate receptor activation. Neuropharmacology 55:447-53

Selected Publications

Oliveira J, Sardinha VM, Guerra-Gomes S, Araque A, Sousa N. Do stars govern our actions? Astrocyte involvement in rodents’ behavior. Trends Neurosci, 38(9):535-549 (2015).

Lima A, Sardinha VM, Oliveira AF, Reis M, Mota C, Silva MA, Marques F, Cerqueira JJ, Pinto L, Sousa N, Oliveira JF. Astrocyte pathology in the prefrontal cortex impairs the cognitive function of rats. Mol Psych, 19:834-841

Teixeira-Castro A, Ailion M, Jalles A, Brignull HR, Vilaça JL, Dias N, Rodrigues P, Oliveira JF, Neves-Carvalho A, Morimoto RI, Maciel P. Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways. Hum Mol Genet. 2011 Aug 1;20(15):2996-3009. doi: 10.1093/hmg/ddr203. Epub 2011 May 5.

Lopes S, Lopes A, Pinto V, Guimarães MR, Sardinha VM, Duarte-Silva S, Pinheiro S, Pizarro J, Oliveira JF, Sousa N, Leite-Almeida H, Sotiropoulos I. Absence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairment. Aging Cell, 15(2):208-216 (2016)

Tavares G, Martins M, Correia JS, Sardinha VM, Guerra-Gomes S, Neves SP das, Marques F, Sousa N, Oliveira JF. Employing an open-source tool to assess astrocyte tridimensional structure. Brain Struct Funct, 222(4):1989-1999 (2017)

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